Keratocyst of the buccal mucosa: case report and immunohistochemical comparative study with sporadic intraosseous keratocystic odontogenic tumor.
Oral Surg Oral Med Oral Pathol Oral Radiol
; 116(5): e387-92, 2013 Nov.
Article
en En
| MEDLINE
| ID: mdl-23669203
ABSTRACT
OBJECTIVES:
Describe a new case of keratocyst of the buccal mucosa and compare its immunohistochemical features with 13 sporadic intraosseous keratocystic odontogenic tumors (KOT). CASE REPORT AND STUDYDESIGN:
A male complaining about an enlargement on the left buccal mucosa was referred to the Stomatology Clinic. Clinical examination revealed a solitary nodule posterior to the parotid papilla. An excisional biopsy was performed following clinical diagnosis of epidermoid cyst. Microscopically, the lesion was characterized by a lining of five cell layers, with columnar basal cells and a corrugated parakeratinized surface. Immunohistochemical reactions for PTCH-1, Smo, Shh, mTOR, bcl-2, Ck17, and Ck19 were performed. PTCH-1 was not expressed in the keratocyst of the buccal mucosa, but was observed in suprabasal layers of eight (61.5%) cases of sporadic intraosseous KOT. Shh, mTOR, bcl-2, Ck17, and Ck19 expression was observed in all the cases investigated.CONCLUSIONS:
The morphology and immunoprofile of this lesion are similar to sporadic intraosseous KOT.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Quistes Odontogénicos
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Tumores Odontogénicos
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Mucosa Bucal
Límite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Oral Surg Oral Med Oral Pathol Oral Radiol
Año:
2013
Tipo del documento:
Article