Triterpenoid saponins with anti-myocardial ischemia activity from the whole plants of Clematis tangutica.
Planta Med
; 79(8): 673-9, 2013 May.
Article
en En
| MEDLINE
| ID: mdl-23670628
ABSTRACT
Four new triterpenoid saponins named clematangosides A-D (1-4) along with six known saponins (5-10) were isolated from the whole plants of Clematis tangutica. Their structures were determined by extensive spectral analysis and chemical evidences. All saponins were evaluated for their protective effects in hypoxia-induced myocardial injury model. Compounds 2-4, 6, and 10 exhibited anti-myocardial ischemia activities with ED50 values in the range of 75.77-127.22 µM.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Saponinas
/
Triterpenos
/
Isquemia Miocárdica
/
Clematis
Idioma:
En
Revista:
Planta Med
Año:
2013
Tipo del documento:
Article