Hypersensitivity reactions to etoposide phosphate.
J Oncol Pharm Pract
; 20(2): 158-60, 2014 Apr.
Article
en En
| MEDLINE
| ID: mdl-23740378
ABSTRACT
Etoposide phosphate is a prodrug of intravenous etoposide recommended for use in patients with demonstrated allergy to etoposide. We have previously published a case series comprising six patients who were successfully treated with etoposide phosphate following preceding etoposide hypersensitivity. In this new paper we now present the cases of two patients who had allergic reactions to both etoposide and etoposide phosphate. As such, we suggest that whilst most patients with etoposide hypersensitivity can safely be treated with etoposide phosphate, a small number are at risk of an additional allergic reaction to etoposide phosphate. Patients being treated for the first time with etoposide phosphate after etoposide allergy should receive their first dose under medical supervision.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Compuestos Organofosforados
/
Hipersensibilidad a las Drogas
/
Etopósido
Límite:
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
J Oncol Pharm Pract
Asunto de la revista:
FARMACIA
Año:
2014
Tipo del documento:
Article
País de afiliación:
Reino Unido