Synthesis of spirocarbamate oxindoles via intramolecular trapping of a ß-silyl carbocation by an N-Boc group.
Org Lett
; 15(13): 3218-21, 2013 Jul 05.
Article
en En
| MEDLINE
| ID: mdl-23758331
ABSTRACT
We report the Lewis acid catalyzed additions of allylsilanes to N-Boc-iminooxindoles and the formation of novel silicon-containing spirocarbamates via intramolecular trapping of a ß-silyl carbocation by an N-Boc group. Several transformations display the synthetic utility of these spirocarbamate oxindoles, including a reductive cyclization to access new silylated furoindoline derivatives.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Silanos
/
Compuestos de Espiro
/
Carbamatos
/
Cationes
/
Ésteres del Ácido Fórmico
/
Indoles
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos