Evaluation of tissue response to Gore-Tex (expanded polytetrafluoroethylene) implantation.
J Craniofac Surg
; 24(4): 1428-30, 2013 Jul.
Article
en En
| MEDLINE
| ID: mdl-23851824
ABSTRACT
OBJECTIVE/HYPOTHESIS:
The aim of this study was to assess the tissue response to Gore-Tex (expanded polytetrafluoroethylene) in rats and compare the results of surgical placement modalities. STUDYDESIGN:
Prospective animal study. MATERIALS ANDMETHODS:
Experiments were performed in 18 young Sprague-Dawley rats that were divided into 3 groups. Gore-Tex patches were implanted subcutaneously over the periosteum in the first group and under the periosteum in the other groups. Gore-Tex was immersed in an antibiotic-containing solution in the third group. All animals were killed 4 weeks after the procedure. The tissue samples were stained with hematoxylin and eosin stain and evaluated using a light microscope.RESULTS:
The Gore-Tex patches were displaced and not observed at the originally implanted sites in the first group. The Gore-Tex patches were observed at the originally implanted sites in the other groups. In group 1, edema and inflammation were prominent. In the second group, ossification was detected in 5 rats and foreign-body reaction and edema were identified in 1 rat. In the third group, all of the rats were found to have developed ossification, but no inflammatory reactions were observed.CONCLUSIONS:
The results suggest that implanting synthetic graft materials immersed in an antibiotic solution at the subperiosteal plane provides better stabilization and low complication rates.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Politetrafluoroetileno
/
Materiales Biocompatibles
/
Implantación de Prótesis
Tipo de estudio:
Etiology_studies
Límite:
Animals
Idioma:
En
Revista:
J Craniofac Surg
Asunto de la revista:
ODONTOLOGIA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Turquía