[The preliminary study of HBV genotype distribution and the relationship with clinical manifestation].
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi
; 27(1): 39-41, 2013 Feb.
Article
en Zh
| MEDLINE
| ID: mdl-23855127
ABSTRACT
OBJECTIVE:
To explore the relationship between HBV genotypes distribution in hepatitis B patients and clinical manifestations in Beijing area.METHODS:
200 HBsAg positive serum were choosen from 1148 serum samples. useing of nested PCR amplification method, HBV DNA S genes were Sequencing and typing; genotype distribution and the relationship with the clinical manifestation were Statistical analysis.RESULTS:
In Beijing area, HBV has B, C, D three genotypes, including B gene type 17 cases (12. 5%), C genotype 116 cases (85.2%), D genotype 3 cases (0.02%); in the carriers, patients with chronic hepatitis B, cirrhosis, liver cancer, B type have been gradually falling, C type have been gradually rising trend.CONCLUSION:
Serious liver disease relate with C type, B type patients with HBV infection is better than C type patients in clinical prognosis and antivirus treatment response.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
ADN Viral
/
Virus de la Hepatitis B
/
Hepatitis B Crónica
Límite:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi
Asunto de la revista:
VIROLOGIA
Año:
2013
Tipo del documento:
Article
País de afiliación:
China