Influence of mutation in cj0183 and cj0588 genes for colonization abilities of Campylobacter jejuni in Caco-2 cells using confocal laser scanning microscope.
Pol J Vet Sci
; 16(2): 387-9, 2013.
Article
en En
| MEDLINE
| ID: mdl-23971210
The cj0183 and cj0588 genes identified in the Campylobacter jejuni NCTC 11168 genome encode proteins with homology to virulence factors found in other bacteria. Previous studies showed that single mutation in the cj0183 gene does not affect adhesion of C. jejuni to the Caco-2 cell line whereas protein encoded by cj0588 is involved in adherence to the Caco-2 cells. In the presented study differences in invasion index were observed between mutants in both genes and single mutation of cj0588 in 81116 and 81-176 C. jejuni strains This fact indicates that Cj0183 protein might play some role in invasion of bacteria into host cells.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteínas Bacterianas
/
Regulación Bacteriana de la Expresión Génica
/
Campylobacter jejuni
/
Células Epiteliales
Tipo de estudio:
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Pol J Vet Sci
Asunto de la revista:
MEDICINA VETERINARIA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Polonia
Pais de publicación:
Alemania