Incidence and outcome of early acute kidney injury in critically-ill trauma patients.
PLoS One
; 8(10): e77376, 2013.
Article
en En
| MEDLINE
| ID: mdl-24146987
ABSTRACT
OBJECTIVE:
To determine the incidence and effect on mortality of early acute kidney injury in severely injured trauma patients using the Acute Kidney Injury Network creatinine criteria.DESIGN:
A retrospective cohort study of severely injured trauma patients admitted to the shock trauma intensive care unit.SETTING:
Texas Trauma Institute, a state designated level I trauma unit certified by the American College of Surgeons Committee on Trauma. PATIENTS 901 severely injured trauma patients admitted over a 15 month period to the shock trauma intensive care unit.INTERVENTIONS:
Retrospective analysis of prospectively collected data abstracted from an electronic trauma database. MEASUREMENTS AND MAINRESULTS:
Of 901 eligible patients admitted to the shock trauma intensive care unit after traumatic injury, 54 patients (6%) developed acute kidney injury, of whom 10 (19%) required renal replacement therapy. The 30-day mortality rate for the entire cohort was 83/901 (9.2%). Patients with early acute kidney injury had a mortality rate of 16/54 (29.6%). When corrected for multiple covariates including injury severity scores, the development of early acute kidney injury was associated with a significantly higher risk of death at 30 days with an OR of 3.4 (95% CI 1.6-7.4).CONCLUSIONS:
Applying the Acute Kidney Injury Network creatinine criteria in severely injured trauma patients, the incidence of early acute kidney injury was 6%. After correction for injury severity, development of early acute kidney injury was independently associated with significantly higher 30-day mortality.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Heridas y Lesiones
/
Enfermedad Crítica
/
Lesión Renal Aguda
Tipo de estudio:
Diagnostic_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
PLoS One
Asunto de la revista:
CIENCIA
/
MEDICINA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos