Anticuerpos Antiidiotipos/inmunología; Afinidad de Anticuerpos/inmunología; Polietilenglicoles/metabolismo; Proteínas/inmunología; Animales; Anticuerpos Antiidiotipos/sangre; Anticuerpos Monoclonales/análisis; Anticuerpos Monoclonales/inmunología; Humanos; Polietilenglicoles/química; Conejos

20kDa mPEG-KLH; 5kDa mPEG-KLH; AAALAC; Albumin; Anti-PEG; Anti-PEGs; Association for the Assessment and Accreditation of Laboratory Animal Care; Backbone-specific; D(50); ELISA; EtO-TEG; H and L chains; HO-PEG; IACUC; IC(50); IFN-α; Institutional Animal Care and Use Committee; KLH; Methoxy-specific; Monoclonal; NPC; PEG; PEG20K-KLH; Poly(ethylene glycol); Polyclonal; RI; RSD; SOD; TEG diol and TetraEG are defined in Table 1; UV; anti-PEG antibodies; dilution of serum that corresponds to 50% of maximal binding in a direct ELISA; enzyme-linked immunosorbent assay; heavy and light immunoglobulin chains; human serum albumin; hydroxyPEG; inhibitor concentration that reduces binding to 50% of maximal binding in a competitive ELISA; interferon-α; keyhole limpet hemocyanin; mAU/min; mAb; mPEG; mPEG-KLH; mTEG; milli-absorbance units per minute; monoclonal antibody; monomethoxypoly(ethylene glycol); n-BuO-TEG; p-nitrophenylcarbonate; p-nitrophenylchloroformate; pNPCOCl; poly(ethylene glycol); porcine Cu­Zn superoxide dismutase; refractive index; relative standard deviation=s.d./mean; ultraviolet absorbance. Crown ether