Valproate recovers the inhibitory effect of dexamethasone on the proliferation of the adult dentate gyrus-derived neural precursor cells via GSK-3ß and ß-catenin pathway.

Boku, Shuken; Nakagawa, Shin; Masuda, Takahiro; Nishikawa, Hiroyuki; Kato, Akiko; Takamura, Naoki; Omiya, Yuki; Kitaichi, Yuji; Inoue, Takeshi; Kusumi, Ichiro

Boku, Shuken; Nakagawa, Shin; Masuda, Takahiro; Nishikawa, Hiroyuki; Kato, Akiko; Takamura, Naoki; Omiya, Yuki; Kitaichi, Yuji; Inoue, Takeshi; Kusumi, Ichiro.

Afiliación

Boku S; Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan. Electronic address: shuboku@med.hokudai.ac.jp.
Nakagawa S; Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Masuda T; Pharmaceutical Laboratories, Dainippon Sumitomo Pharma Co. Ltd., Osaka, Japan.
Nishikawa H; Pharmaceutical Laboratories, Dainippon Sumitomo Pharma Co. Ltd., Osaka, Japan.
Kato A; Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Takamura N; Pharmaceutical Laboratories, Dainippon Sumitomo Pharma Co. Ltd., Osaka, Japan.
Omiya Y; Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Kitaichi Y; Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Inoue T; Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Kusumi I; Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

Eur J Pharmacol ; 723: 425-30, 2014 Jan 15.

Article en En | MEDLINE | ID: mdl-24211784

Asunto(s)

Antimaníacos/farmacología; Giro Dentado/citología; Glucógeno Sintasa Quinasa 3/metabolismo; Células-Madre Neurales/efectos de los fármacos; Ácido Valproico/farmacología; beta Catenina/metabolismo; Animales; Proliferación Celular/efectos de los fármacos; Ciclina D1/genética; Dexametasona/farmacología; Glucocorticoides/farmacología; Glucógeno Sintasa Quinasa 3 beta; Inhibidores de Histona Desacetilasas/farmacología; Histona Desacetilasas/metabolismo; Masculino; Células-Madre Neurales/metabolismo; Fosforilación/efectos de los fármacos; ARN Mensajero/metabolismo; Ratas; Ratas Sprague-Dawley

Palabras clave

Glucocorticoid; Hippocampus; Mood disorder; Mood stabilizer; Neurogenesis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ácido Valproico / Antimaníacos / Giro Dentado / Glucógeno Sintasa Quinasa 3 / Beta Catenina / Células-Madre Neurales Límite: Animals Idioma: En Revista: Eur J Pharmacol Año: 2014 Tipo del documento: Article Pais de publicación: Países Bajos

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