Serotonin 1A receptors and sexual behavior in male rats: a review.
Pharmacol Biochem Behav
; 121: 102-14, 2014 Jun.
Article
en En
| MEDLINE
| ID: mdl-24239787
ABSTRACT
Serotonin plays an important role in male sexual behavior. Many studies have been performed on the pivotal role of 5-HT1A receptors in sexual behavior. Overall, 5-HT1A receptors do not appear to be involved under normal circumstances, but become very important under conditions of elevated serotonin levels in sexual behavior. 5-HT1A receptor agonists facilitate ejaculatory behavior in male rats, while inhibiting copulatory behavior. Three different phases can be distinguished in rats' sexual cycle, the introductory (precopulatory), the copulatory and the executive (ejaculatory) phases. Different mechanisms and brain regions are involved in these phases. The mechanisms, brain regions and the possible involvement of 5-HT and 5-HT1A receptors in the appropriate phases in male rat sexual behavior will be discussed in the current review.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Conducta Sexual Animal
/
Receptor de Serotonina 5-HT1A
Límite:
Animals
Idioma:
En
Revista:
Pharmacol Biochem Behav
Año:
2014
Tipo del documento:
Article