Munc18-1 haploinsufficiency results in enhanced anxiety-like behavior as determined by heart rate responses in mice.

Hager, Torben; Maroteaux, Grégoire; Pont, Paula du; Julsing, Joris; van Vliet, Rick; Stiedl, Oliver

Hager, Torben; Maroteaux, Grégoire; Pont, Paula du; Julsing, Joris; van Vliet, Rick; Stiedl, Oliver.

Afiliación

Hager T; Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, The Netherlands; Sylics BV, PO Box 71033, 1008 BA Amsterdam, The Netherlands.
Maroteaux G; Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, The Netherlands.
Pont Pd; Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, The Netherlands.
Julsing J; Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, The Netherlands.
van Vliet R; Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, The Netherlands.
Stiedl O; Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, The Netherlands; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU Universit

Behav Brain Res ; 260: 44-52, 2014 Mar 01.

Article en En | MEDLINE | ID: mdl-24304718

Asunto(s)

Ansiedad/fisiopatología; Frecuencia Cardíaca/fisiología; Proteínas Munc18/metabolismo; Animales; Ansiedad/genética; Percepción Auditiva/fisiología; Ritmo Circadiano/fisiología; Condicionamiento Clásico/fisiología; Extinción Psicológica/fisiología; Miedo/fisiología; Haploinsuficiencia; Masculino; Ratones; Ratones Endogámicos C57BL; Actividad Motora/fisiología; Proteínas Munc18/genética; Reconocimiento en Psicología/fisiología

Palabras clave

ANOVA; ANS; Autonomic measures; CS; Coping style; DFA; Diurnal changes; ECG; Fear conditioning; HR; HRV; HZ; Heart rate variability; Nonlinear analysis; PNS; PTSD; RMSSD; SNAP (Soluble NSF Attachment Protein) Receptor; SNARE; SNS; SPL; US; WT; analysis of variance; autonomic nervous system; beats per minute; bpm; conditioned stimulus; detrended fluctuation analysis; electrocardiogram; heart rate; heart rate variability; heterozygous; parasympathetic nervous system; posttraumatic stress disorder; root mean square successive difference; sound pressure level; sympathetic nervous system; unconditioned stimulus; wild-type

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ansiedad / Proteínas Munc18 / Frecuencia Cardíaca Límite: Animals Idioma: En Revista: Behav Brain Res Año: 2014 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Países Bajos

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