Musculoskeletal changes after 1 year of exercise in older breast cancer survivors.
J Cancer Surviv
; 8(2): 304-11, 2014 Jun.
Article
en En
| MEDLINE
| ID: mdl-24317968
ABSTRACT
INTRODUCTION:
We have previously reported that 1 year of supervised resistance + impact training stopped bone loss and built muscle strength in older breast cancer survivors. The purpose of this study was to determine whether these benefits persisted 1 year after completion of the intervention.METHODS:
Sixty-seven women from the original trial completed baseline and post-intervention body composition and muscle strength tests, and 44 women were available 1 year later for follow-up assessments. Bone mineral density (grams per square centimeter) of the hip and spine, muscle mass (kilograms), and fat mass (kilograms) were measured by dual-energy X-ray absorptiometry and maximal upper and lower body strength were measured by one-repetition maximum tests (kilograms). We compared between group changes across baseline (pre-intervention), 1 (post-intervention), and 2 years (1 year follow up) on study outcomes using repeated-measures analysis of covariance, adjusting for age.RESULTS:
Significant group by time interactions were found for spine bone mineral density (BMD) (p < 0.01) and lower body muscle strength (p < 0.05), with a trend for upper body muscle strength (p = 0.05). Spine BMD remained stable across intervention and follow-up periods in exercisers compared with continuous losses in controls across 1- and 2-year periods. In contrast, lower body strength increased in exercisers across the intervention, but decreased to near-baseline levels during follow-up compared with no change over either time period in controls.CONCLUSIONS:
Our data suggest that spine BMD can be preserved in older breast cancer survivors even after formal exercise training stops; however, muscle strength is not similarly maintained and may require continued participation in a supervised exercise program. IMPLICATIONS FOR CANCER SURVIVORS Exercise programs aimed at improving musculoskeletal health should be considered in the long-term care plan for breast cancer survivors.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Composición Corporal
/
Neoplasias de la Mama
/
Ejercicio Físico
/
Densidad Ósea
/
Sobrevivientes
/
Fuerza Muscular
Tipo de estudio:
Clinical_trials
/
Guideline
Límite:
Aged
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
J Cancer Surviv
Año:
2014
Tipo del documento:
Article