[The effect of polymorphism F279Y of GHR gene on milk production trait in Chinese Holstein cattle].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
; 29(5): 400-4, 2013 Sep.
Article
en Zh
| MEDLINE
| ID: mdl-24386811
ABSTRACT
OBJECTIVE:
To study the effect of the polymorphism F279Y of the growth hormone receptor (GHR) gene on milk yield and composition in Chinese Holstein cattle.METHODS:
Hundred thirty two Chinese Holstein cattle were selected as study materials, according to DHI production performance method to get the data of milk yield and composition; PCR- SSCP and sequencing method were used to detect the genotypes; least square method was used to acquire correlation analysis.RESULTS:
Chinese Holstein cattle F279Y of GHR gene loci A and T allele frequency were 0.68 and 0.32, respectively, the experimental group significantly deviated from Hardy Weinberg equilibrium (P < 0.01); 305 d milk yield of AA genotype was significantly higher than AT type (P < 0.05), 305 d milk fat yield, 305 d milk protein yield and 305 d lactose of AT type had better trend than those of AA type in numeric; Therefore, allele A was dominant gene of high milk yield, allele T has positive effect on milk composition.CONCLUSION:
Mutation F279Y of GHR gene can be used as genetic markers in Chinese Holstein milk production traits of marker assisted selection (MAS) breeding.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Receptores de Somatotropina
/
Bovinos
/
Mutación Puntual
/
Leche
Límite:
Animals
Idioma:
Zh
Revista:
Zhongguo Ying Yong Sheng Li Xue Za Zhi
Asunto de la revista:
FISIOLOGIA
Año:
2013
Tipo del documento:
Article
País de afiliación:
China