Corneal biomechanical properties and associated factors in school-age children.

ABSTRACT

PURPOSE: To study and analyze the correlation among corneal biomechanical properties and associated factors including central corneal thickness (CCT), corneal curvature (CT), and intraocular pressure (IOP) in school-age children. METHODS: A cross sectional investigation was conducted. An ocular response analyzer was utilized to assess the corneal biomechanical properties, such as corneal hysteresis and corneal resistance factors, in children of school age. Multivariate regression analysis was used to investigate the relationship between corneal biomechanical properties and other ocular parameters including CCT, corneal curvature (k1 and k2), and IOP. The right eyes of all subjects were selected for statistical analysis. RESULTS: A total of 571 children were enrolled 303 male and 268 female, with an average age of 10.47 +/- 1.0 years. The mean value of corneal hysteresis was 10.98 +/- 1.78 mmHg, corneal resistance factor was 11.46 +/-1.69 mmHg, and CCT was 556.01 +/- 28.97, microm. CONCLUSION: The feasibility of corneal biomechanical detection in school age children was validated. This study provides fundamental data on corneal biomechanical properties in school-age children and associated factors.