Therapeutic approaches against common structural features of toxic oligomers shared by multiple amyloidogenic proteins.

Guerrero-Muñoz, Marcos J; Castillo-Carranza, Diana L; Kayed, Rakez

Guerrero-Muñoz, Marcos J; Castillo-Carranza, Diana L; Kayed, Rakez.

Afiliación

Guerrero-Muñoz MJ; Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, Galveston, TX, USA; Departments of Neurology, Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX, USA.
Castillo-Carranza DL; Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, Galveston, TX, USA; Departments of Neurology, Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX, USA.
Kayed R; Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, Galveston, TX, USA; Departments of Neurology, Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX, USA. Electronic address: rakayed@utmb.edu.

Biochem Pharmacol ; 88(4): 468-78, 2014 Apr 15.

Article en En | MEDLINE | ID: mdl-24406245

Asunto(s)

Proteínas Amiloidogénicas/química; Biopolímeros/química; Proteínas Amiloidogénicas/toxicidad; Animales; Biopolímeros/toxicidad; Inmunoterapia; Ratones

Palabras clave

Amyloid oligomers; Anle138b (http://www.cipsm.de/en/publications/researchAreaA/2013/Anle138b_a_novel_oligomer_modulator_for_disease-modifying_therapy_of_neurodegenerative_diseases_such_as_prion_and_Parkinson_s_disease/index.html?style=1); Anti-amyloid small molecules; Baicalein (PubChem CID: 5281605); CLR01 (http://www.med-chemist.com/2012/11/clr01-effectively-inhibits.html); Curcumin (PubChem CID: 969516); Epigallocatechingallate (PubChem CID: 65064); Immunotherapy; Methylene blue (PubChem CID: 6099); Oleuropein (PubChem CID: 5281544); Phenol Red (PubChem CID: 4766); Resveratrol (PubChem CID: 445154); Silibinin (PubChem CID: 31553)

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biopolímeros / Proteínas Amiloidogénicas Límite: Animals Idioma: En Revista: Biochem Pharmacol Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

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