Treatment of multiple solitary plasmacytomas with cytokine-induced killer cells.
Cytotherapy
; 16(2): 278-84, 2014 Feb.
Article
en En
| MEDLINE
| ID: mdl-24438905
ABSTRACT
BACKGROUND AIMS:
Currently available treatment methods for advanced plasmacytoma include surgery, chemotherapy, radiotherapy, immunomodulatory agents, hematopoietic stem cell transplantation and donor lymphocyte infusion. We report a case of advanced refractory multiple solitary plasmacytomas in a 68-year-old Asian man with multiple bone lesions, in whom autologous cytokine-induced killer (CIK) cells were administered in an effort to eliminate residual tumor lesions.METHODS:
CIK cells were infused monthly for 21 courses.RESULTS:
The patient has survived 63 months since the first hospital visit without disease progression for 40 months.CONCLUSIONS:
This case represents the first report of autologous CIK cell immunotherapy used successfully to suppress multiple solitary plasmacytomas and resolve bone lesions.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Plasmacitoma
/
Neoplasias Óseas
/
Trasplante de Células Madre Hematopoyéticas
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Vacunas contra el Cáncer
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Células Asesinas Inducidas por Citocinas
/
Inmunoterapia
Límite:
Aged
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Humans
/
Male
Idioma:
En
Revista:
Cytotherapy
Asunto de la revista:
TERAPEUTICA
Año:
2014
Tipo del documento:
Article
País de afiliación:
China