A case of Degos disease: demonstration of C5b-9-mediated vascular injury.
Mod Rheumatol
; 25(3): 480-3, 2015 May.
Article
en En
| MEDLINE
| ID: mdl-24506660
ABSTRACT
A 68-year-old Japanese male presented with atrophic erythematous white lesions with peripheral dark reddish rims on his back. Multiple ulcers were detected from his stomach to his large intestine using endoscopy. Although the patient was given high doses of a steroid, aspirin, dipyridamole, and intravenous immunoglobulin therapy, he died of gastrointestinal hemorrhage, perforation and septic shock. An autopsy examination revealed pauci-inflammatory thrombotic microangiopathy with endothelial cell injury, fibrous occlusive arteriopathy, and vascular C5b-9 deposition in the wall of the gastrointestinal tract from the esophagus to the large intestine as well as in the dermis of the skin.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Piel
/
Complejo de Ataque a Membrana del Sistema Complemento
/
Tracto Gastrointestinal
/
Papulosis Atrófica Maligna
Límite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Mod Rheumatol
Año:
2015
Tipo del documento:
Article
País de afiliación:
Japón