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The two active X chromosomes in female ESCs block exit from the pluripotent state by modulating the ESC signaling network.
Schulz, Edda G; Meisig, Johannes; Nakamura, Tomonori; Okamoto, Ikuhiro; Sieber, Anja; Picard, Christel; Borensztein, Maud; Saitou, Mitinori; Blüthgen, Nils; Heard, Edith.
Afiliación
  • Schulz EG; Mammalian Developmental Epigenetics Group, Institut Curie, CNRS UMR 3215, INSERM U934, Paris 75248, France. Electronic address: edda.schulz@curie.fr.
  • Meisig J; Institute of Pathology, Charité-Universitätsmedizin, 10117 Berlin, Germany; Integrative Research Institute for the Life Sciences and Institute for Theoretical Biology, Humboldt Universität, 10115 Berlin, Germany.
  • Nakamura T; Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan; JST, ERATO, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.
  • Okamoto I; Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan; JST, ERATO, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.
  • Sieber A; Institute of Pathology, Charité-Universitätsmedizin, 10117 Berlin, Germany; Integrative Research Institute for the Life Sciences and Institute for Theoretical Biology, Humboldt Universität, 10115 Berlin, Germany.
  • Picard C; Mammalian Developmental Epigenetics Group, Institut Curie, CNRS UMR 3215, INSERM U934, Paris 75248, France.
  • Borensztein M; Mammalian Developmental Epigenetics Group, Institut Curie, CNRS UMR 3215, INSERM U934, Paris 75248, France.
  • Saitou M; Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan; JST, ERATO, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan; Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho, Shogoin Yoshida,
  • Blüthgen N; Institute of Pathology, Charité-Universitätsmedizin, 10117 Berlin, Germany; Integrative Research Institute for the Life Sciences and Institute for Theoretical Biology, Humboldt Universität, 10115 Berlin, Germany.
  • Heard E; Mammalian Developmental Epigenetics Group, Institut Curie, CNRS UMR 3215, INSERM U934, Paris 75248, France. Electronic address: edith.heard@curie.fr.
Cell Stem Cell ; 14(2): 203-16, 2014 Feb 06.
Article en En | MEDLINE | ID: mdl-24506884
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromosoma X / Transducción de Señal / Células Madre Pluripotentes / Células Madre Embrionarias Límite: Animals Idioma: En Revista: Cell Stem Cell Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromosoma X / Transducción de Señal / Células Madre Pluripotentes / Células Madre Embrionarias Límite: Animals Idioma: En Revista: Cell Stem Cell Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos