The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses.

Khare, Sonal; Ratsimandresy, Rojo A; de Almeida, Lúcia; Cuda, Carla M; Rellick, Stephanie L; Misharin, Alexander V; Wallin, Melissa C; Gangopadhyay, Anu; Forte, Eleonora; Gottwein, Eva; Perlman, Harris; Reed, John C; Greaves, David R; Dorfleutner, Andrea; Stehlik, Christian

Khare, Sonal; Ratsimandresy, Rojo A; de Almeida, Lúcia; Cuda, Carla M; Rellick, Stephanie L; Misharin, Alexander V; Wallin, Melissa C; Gangopadhyay, Anu; Forte, Eleonora; Gottwein, Eva; Perlman, Harris; Reed, John C; Greaves, David R; Dorfleutner, Andrea; Stehlik, Christian.

Afiliación

Khare S; Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Ratsimandresy RA; Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
de Almeida L; Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Cuda CM; Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Rellick SL; 1] Program in Cancer Cell Biology, Health Sciences Center, West Virginia University, Morgantown, West Virginia, USA. [2] Present address: Center for Neuroscience, Health Sciences Center, West Virginia University, Morgantown, West Virginia, USA.
Misharin AV; Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Wallin MC; Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Gangopadhyay A; Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Forte E; Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Gottwein E; Department of Microbiology and Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Perlman H; Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Reed JC; 1] Apoptosis and Cell Death Research Program, Sanford-Burnham Medical Research Institute, La Jolla, California, USA. [2] Pharma Research and Early Development, F. Hoffmann-La Roche, Basel, Switzerland.
Greaves DR; Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Dorfleutner A; Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Stehlik C; 1] Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA. [2] Robert H. Lurie Comprehensive Cancer Center, Interdepartmental Immunobiology Center and Skin Disease Research Center, Feinberg School of Medicine, Northwestern Unive

Nat Immunol ; 15(4): 343-53, 2014 Apr.

Article en En | MEDLINE | ID: mdl-24531343

Asunto(s)

Proteínas Adaptadoras Transductoras de Señales/metabolismo; Proteínas Portadoras/metabolismo; Infecciones por Virus ADN/inmunología; Virus ADN/inmunología; Inflamasomas/metabolismo; Macrófagos/inmunología; Proteínas Nucleares/metabolismo; Proteínas Adaptadoras Transductoras de Señales/genética; Secuencia de Aminoácidos; Animales; Proteínas Portadoras/genética; Caspasa 1/metabolismo; Proteínas de Unión al ADN; Células HEK293; Humanos; Inmunidad/genética; Interferón Tipo I/genética; Interferón Tipo I/inmunología; Interferón gamma/genética; Interferón gamma/inmunología; Ratones; Ratones Endogámicos C57BL; Ratones Transgénicos; Datos de Secuencia Molecular; Complejos Multiproteicos/genética; Complejos Multiproteicos/metabolismo; Unión Proteica/genética; Estructura Terciaria de Proteína/genética; Alineación de Secuencia; Transgenes/genética; Proteínas Virales/genética; Homóloga LST8 de la Proteína Asociada al mTOR

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Nucleares / Proteínas Portadoras / Proteínas Adaptadoras Transductoras de Señales / Infecciones por Virus ADN / Virus ADN / Inflamasomas / Macrófagos Límite: Animals / Humans Idioma: En Revista: Nat Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google