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Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma.
Borad, Mitesh J; Champion, Mia D; Egan, Jan B; Liang, Winnie S; Fonseca, Rafael; Bryce, Alan H; McCullough, Ann E; Barrett, Michael T; Hunt, Katherine; Patel, Maitray D; Young, Scott W; Collins, Joseph M; Silva, Alvin C; Condjella, Rachel M; Block, Matthew; McWilliams, Robert R; Lazaridis, Konstantinos N; Klee, Eric W; Bible, Keith C; Harris, Pamela; Oliver, Gavin R; Bhavsar, Jaysheel D; Nair, Asha A; Middha, Sumit; Asmann, Yan; Kocher, Jean-Pierre; Schahl, Kimberly; Kipp, Benjamin R; Barr Fritcher, Emily G; Baker, Angela; Aldrich, Jessica; Kurdoglu, Ahmet; Izatt, Tyler; Christoforides, Alexis; Cherni, Irene; Nasser, Sara; Reiman, Rebecca; Phillips, Lori; McDonald, Jackie; Adkins, Jonathan; Mastrian, Stephen D; Placek, Pamela; Watanabe, Aprill T; Lobello, Janine; Han, Haiyong; Von Hoff, Daniel; Craig, David W; Stewart, A Keith; Carpten, John D.
Afiliación
  • Borad MJ; Division of Hematology/Oncology Mayo Clinic, Scottsdale, Arizona, United States of America ; Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America ; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Champion MD; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America ; Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America.
  • Egan JB; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Liang WS; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Fonseca R; Division of Hematology/Oncology Mayo Clinic, Scottsdale, Arizona, United States of America ; Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America ; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Bryce AH; Division of Hematology/Oncology Mayo Clinic, Scottsdale, Arizona, United States of America ; Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America ; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
  • McCullough AE; Department of Pathology, Mayo Clinic, Scottsdale, Arizona, United States of America.
  • Barrett MT; Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America ; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Hunt K; Division of Hematology/Oncology Mayo Clinic, Scottsdale, Arizona, United States of America.
  • Patel MD; Department of Radiology, Mayo Clinic, Scottsdale, Arizona, United States of America.
  • Young SW; Department of Radiology, Mayo Clinic, Scottsdale, Arizona, United States of America.
  • Collins JM; Department of Radiology, Mayo Clinic, Scottsdale, Arizona, United States of America.
  • Silva AC; Department of Radiology, Mayo Clinic, Scottsdale, Arizona, United States of America.
  • Condjella RM; Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America.
  • Block M; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America ; Mayo Clinic Cancer Center, Rochester, Minnesota, United States of America.
  • McWilliams RR; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America ; Mayo Clinic Cancer Center, Rochester, Minnesota, United States of America.
  • Lazaridis KN; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Klee EW; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America ; Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America.
  • Bible KC; Mayo Clinic Cancer Center, Rochester, Minnesota, United States of America.
  • Harris P; Investigational Drug Branch, National Cancer Institute, Rockville, Maryland, United States of America.
  • Oliver GR; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America ; Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America.
  • Bhavsar JD; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America ; Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America.
  • Nair AA; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America ; Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America.
  • Middha S; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America ; Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America.
  • Asmann Y; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America ; Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America.
  • Kocher JP; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America ; Department of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, United States of America.
  • Schahl K; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Kipp BR; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Barr Fritcher EG; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Baker A; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Aldrich J; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Kurdoglu A; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Izatt T; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Christoforides A; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Cherni I; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Nasser S; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Reiman R; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Phillips L; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • McDonald J; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Adkins J; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Mastrian SD; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Placek P; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Watanabe AT; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Lobello J; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Han H; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Von Hoff D; Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America ; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Craig DW; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
  • Stewart AK; Division of Hematology/Oncology Mayo Clinic, Scottsdale, Arizona, United States of America ; Mayo Clinic Cancer Center, Scottsdale, Arizona, United States of America ; Center for Individualized Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Carpten JD; Translational Genomics Research Institute, Phoenix, Arizona, United States of America.
PLoS Genet ; 10(2): e1004135, 2014 Feb.
Article en En | MEDLINE | ID: mdl-24550739
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de los Conductos Biliares / Transducción de Señal / Colangiocarcinoma / Receptor Tipo 2 de Factor de Crecimiento de Fibroblastos / Receptores ErbB Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de los Conductos Biliares / Transducción de Señal / Colangiocarcinoma / Receptor Tipo 2 de Factor de Crecimiento de Fibroblastos / Receptores ErbB Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos