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The prenatal origins of cancer.
Marshall, Glenn M; Carter, Daniel R; Cheung, Belamy B; Liu, Tao; Mateos, Marion K; Meyerowitz, Justin G; Weiss, William A.
Afiliación
  • Marshall GM; Kids Cancer Centre, Sydney Children's Hospital, Randwick 2031, New South Wales, Australia; and the Children's Cancer Institute Australia for Medical Research, Lowy Cancer Centre, University of New South Wales, Randwick 2031, Australia.
  • Carter DR; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Centre, University of New South Wales, Randwick 2031, Australia.
  • Cheung BB; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Centre, University of New South Wales, Randwick 2031, Australia.
  • Liu T; Children's Cancer Institute Australia for Medical Research, Lowy Cancer Centre, University of New South Wales, Randwick 2031, Australia.
  • Mateos MK; Kids Cancer Centre, Sydney Children's Hospital, Randwick 2031, New South Wales, Australia; and the Children's Cancer Institute Australia for Medical Research, Lowy Cancer Centre, University of New South Wales, Randwick 2031, Australia.
  • Meyerowitz JG; Department of Neurology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, USA.
  • Weiss WA; Department of Neurology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, USA.
Nat Rev Cancer ; 14(4): 277-89, 2014 04.
Article en En | MEDLINE | ID: mdl-24599217
ABSTRACT
The concept that some childhood malignancies arise from postnatally persistent embryonal cells has a long history. Recent research has strengthened the links between driver mutations and embryonal and early postnatal development. This evidence, coupled with much greater detail on the cell of origin and the initial steps in embryonal cancer initiation, has identified important therapeutic targets and provided renewed interest in strategies for the early detection and prevention of childhood cancer.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cerebelosas / Meduloblastoma / Neuroblastoma Tipo de estudio: Etiology_studies / Prognostic_studies / Screening_studies Límite: Animals / Child / Female / Humans / Pregnancy Idioma: En Revista: Nat Rev Cancer Asunto de la revista: NEOPLASIAS Año: 2014 Tipo del documento: Article País de afiliación: Australia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cerebelosas / Meduloblastoma / Neuroblastoma Tipo de estudio: Etiology_studies / Prognostic_studies / Screening_studies Límite: Animals / Child / Female / Humans / Pregnancy Idioma: En Revista: Nat Rev Cancer Asunto de la revista: NEOPLASIAS Año: 2014 Tipo del documento: Article País de afiliación: Australia