Abuse and diversion of buprenorphine sublingual tablets and film.
J Subst Abuse Treat
; 47(1): 27-34, 2014 Jul.
Article
en En
| MEDLINE
| ID: mdl-24680219
ABSTRACT
Buprenorphine abuse is common worldwide. Rates of abuse and diversion of three sublingual buprenorphine formulations (single ingredient tablets; naloxone combination tablets and film) were compared. Data were obtained from the Researched Abuse, Diversion, and Addiction-Related Surveillance (RADARS) System Poison Center, Drug Diversion, Opioid Treatment (OTP), Survey of Key Informants' Patients (SKIP), and College Survey Programs through December 2012. To control for drug availability, event ratios (rates) were calculated quarterly, based on the number of patients filling prescriptions for each formulation ("unique recipients of a dispensed drug," URDD) and averaged and compared using negative binomial regression. Abuse rates in the OTP, SKIP, and College Survey Programs were greatest for single ingredient tablets, and abuse rates in the Poison Center Program and illicit diversion rates were greatest for the combination tablets. Combination film rates were significantly less than rates for either tablet formulation in all programs. No geographic pattern could be discerned.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Buprenorfina
/
Desvío de Medicamentos bajo Prescripción
/
Trastornos Relacionados con Opioides
/
Narcóticos
Límite:
Humans
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Subst Abuse Treat
Asunto de la revista:
TRANSTORNOS RELACIONADOS COM SUBSTANCIAS
Año:
2014
Tipo del documento:
Article