A new xanthone derivative from twigs of Garcinia nobilis.
Nat Prod Res
; 28(14): 1030-6, 2014.
Article
en En
| MEDLINE
| ID: mdl-24697710
ABSTRACT
Phytochemical investigation of the twigs of Garcinia nobilis led to the isolation of a new xanthone, named l-hydroxy-2,5-dimethoxyxanthone (1), together with 15 known compounds (2-16). The structures of the new and known compounds were established by means of spectroscopic methods and by comparison with previously reported data. The structure of compound 1 was confirmed by X-ray diffraction data. Compounds 1-16 were tested for their cytotoxic activity against human cervix carcinoma cell line KB-3-1. Compounds 5 and 11 showed moderate activity while others showed weak biological activity in these cytotoxicity assays. Compounds 4 and 9 were found to be inactive.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Garcinia
/
Xantonas
/
Antineoplásicos Fitogénicos
Límite:
Humans
País/Región como asunto:
Africa
Idioma:
En
Revista:
Nat Prod Res
Año:
2014
Tipo del documento:
Article
País de afiliación:
Camerún