The identification of a novel SIRT6 modulator from Trigonella foenum-graecum using ligand fishing with protein coated magnetic beads.

Singh, N; Ravichandran, S; Spelman, K; Fugmann, S D; Moaddel, R

Singh, N; Ravichandran, S; Spelman, K; Fugmann, S D; Moaddel, R.

Afiliación

Singh N; Biomedical Research Center, National institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Suite 100, Baltimore, MD 21224, USA.
Ravichandran S; Advanced Biomedical Computing Center, Information Systems Program, Frederick National Laboratory for Cancer Research (FNLCR), Frederick, MD 21702, USA.
Spelman K; Health, Education & Research in Botanical Medicine, 2209 Dollarhide Way, Ashland, OR 97520, USA.
Fugmann SD; Department of Biomedical Sciences, Chang Gung University, 259 Wen-Hwa 1st Road, Kwei-Shan, Taiwan.
Moaddel R; Biomedical Research Center, National institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Suite 100, Baltimore, MD 21224, USA. Electronic address: moaddelru@grc.nia.nih.gov.

J Chromatogr B Analyt Technol Biomed Life Sci ; 968: 105-11, 2014 Oct 01.

Article en En | MEDLINE | ID: mdl-24704183

Asunto(s)

Magnetismo/métodos; Imanes/química; Extractos Vegetales/química; Sirtuinas/metabolismo; Trigonella/química; Escherichia coli/metabolismo; Ligandos; Semillas/química

Palabras clave

Fenugreek seed extract; Ligand fishing; Magnetic beads; Orientin; SIRT6

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Extractos Vegetales / Trigonella / Sirtuinas / Imanes / Magnetismo Tipo de estudio: Diagnostic_studies Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Asunto de la revista: ENGENHARIA BIOMEDICA Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Países Bajos

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