A conditional knockout mouse model reveals endothelial cells as the principal and possibly exclusive source of plasma factor VIII.

Fahs, Scot A; Hille, Matthew T; Shi, Qizhen; Weiler, Hartmut; Montgomery, Robert R

Fahs, Scot A; Hille, Matthew T; Shi, Qizhen; Weiler, Hartmut; Montgomery, Robert R.

Afiliación

Fahs SA; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI;
Hille MT; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI;
Shi Q; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI; Medical College of Wisconsin, Milwaukee, WI; and Children's Research Institute, Children's Hospital of Wisconsin, Milwaukee, WI.
Weiler H; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI; Medical College of Wisconsin, Milwaukee, WI; and.
Montgomery RR; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI; Medical College of Wisconsin, Milwaukee, WI; and Children's Research Institute, Children's Hospital of Wisconsin, Milwaukee, WI.

Blood ; 123(24): 3706-13, 2014 Jun 12.

Article en En | MEDLINE | ID: mdl-24705491

Asunto(s)

Células Endoteliales/metabolismo; Factor VIII/biosíntesis; Animales; Trasplante de Médula Ósea; Células Cultivadas; Factor VIII/análisis; Factor VIII/genética; Femenino; Genotipo; Hígado/metabolismo; Masculino; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; Distribución Tisular

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor VIII / Células Endoteliales Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Blood Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos

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