Synthesis, LSD1 Inhibitory Activity, and LSD1 Binding Model of Optically Pure Lysine-PCPA Conjugates.

Itoh, Yukihiro; Ogasawara, Daisuke; Ota, Yosuke; Mizukami, Tamio; Suzuki, Takayoshi

Itoh, Yukihiro; Ogasawara, Daisuke; Ota, Yosuke; Mizukami, Tamio; Suzuki, Takayoshi.

Afiliación

Itoh Y; Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 13 Taishogun Nishitakatsukasa-cho, Kita-ku, Kyoto 603-8334, Japan.
Ogasawara D; Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 13 Taishogun Nishitakatsukasa-cho, Kita-ku, Kyoto 603-8334, Japan.
Ota Y; Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 13 Taishogun Nishitakatsukasa-cho, Kita-ku, Kyoto 603-8334, Japan.
Mizukami T; Graduate School of Bio-Science, Nagahama Institute of Bio-Science Technology, 1226 Tamura-cho, Nagahama, Shiga 526-0829, Japan.
Suzuki T; Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 13 Taishogun Nishitakatsukasa-cho, Kita-ku, Kyoto 603-8334, Japan ; PRESTO, Japan Science and Technology Agency (JST), 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan.

Comput Struct Biotechnol J ; 9: e201402002, 2014.

Article en En | MEDLINE | ID: mdl-24757500

Palabras clave

drug discovery; epigenetics; histone demethylase; ligand-protein interaction; lysine-specific demethylase; protein-targeted drug delivery

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Comput Struct Biotechnol J Año: 2014 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos

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