Primary splenic angiosarcoma associated with anemia, leukocytosis and thrombocytopenia.
Ann Clin Lab Sci
; 44(2): 217-21, 2014.
Article
en En
| MEDLINE
| ID: mdl-24795063
ABSTRACT
Primary angiosarcoma of the spleen is a rare neoplasm arising from endothelial cells. It is an aggressive neoplasm with a poor prognosis. We report a case of 61-year-old Caucasian man who presented with shortness of breath, anemia, leukocytosis, and thrombocytopenia. Ultrasound Sonogram (US) and Computed Tomography (CT) scans revealed a massively enlarged spleen with numerous enhancing hypodense lesions. The spleen was adherent to the omentum, retroperitoneum, and tail of the pancreas. Image-guided Fine Needle Aspiration (FNA) revealed an atypical spindle cell lesion. Resection of the spleen and attached tail of pancreas was performed. Histological examination and immunohistochemical studies revealed a diffuse vascular malignant neoplasm with features of angiosarcoma. The patient appeared disease free after resection. He died within 5 months of unknown etiology.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias del Bazo
/
Trombocitopenia
/
Anemia
/
Hemangiosarcoma
/
Leucocitosis
Tipo de estudio:
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Ann Clin Lab Sci
Año:
2014
Tipo del documento:
Article