Antibacterial and cytotoxic activity of ethanol extract of mikania cordata (burm.f.) B.L. Robinson leaves.
J Basic Clin Pharm
; 2(2): 103-7, 2011 Mar.
Article
en En
| MEDLINE
| ID: mdl-24826008
ABSTRACT
The purpose of the present study to examine the antibacterial and cytotoxic properties of ethanol extract of leaves of Mikania cordata (Burm.f.) B.L. Robinson. To determine antibacterial activities, the extract was tested against four Gram positive and six Gram negative bacteria at three concentrations (500, 800, 1000 µg disc(-1)) through disc diffusion method. The extract showed moderate antibacterial actions and that was increased by increasing the concentration of the sample. The maximum antimicrobial potential was obtained against Shigella flexneri and no sen sitivity was found for Klebsiella sp. Comparatively gram-positive bacteria demonstrated more susceptibility to the extract than gram-negative bacteria. Cytotoxic property of the sample was done using Brine shrimp lethality bioassay where it did not show noticeable toxicity. So, our present study reveals that the leaves extract of M. cordata possess considerable antibacterial properties along with lesser amount of cytotoxicity.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
J Basic Clin Pharm
Año:
2011
Tipo del documento:
Article
País de afiliación:
Bangladesh