Catalytic enantioselective Nazarov cyclization: construction of vicinal all-carbon-atom quaternary stereocenters.
Angew Chem Int Ed Engl
; 53(24): 6180-3, 2014 Jun 10.
Article
en En
| MEDLINE
| ID: mdl-24838340
ABSTRACT
The diastereoselective asymmetric synthesis of vicinal all-carbon-atom quaternary stereocenters is a challenging problem in organic synthesis for which only few solutions have been described. A catalytic asymmetric Nazarov cyclization of fully substituted dienones that provides cyclopentenone derivatives with vicinal quaternary stereocenters in high optical purity and as single diastereoisomers is now reported.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Carbono
Idioma:
En
Revista:
Angew Chem Int Ed Engl
Año:
2014
Tipo del documento:
Article