The novel pterostilbene derivative ANK-199 induces autophagic cell death through regulating PI3 kinase class III/beclin 1/Atg­related proteins in cisplatin­resistant CAR human oral cancer cells.

Hsieh, Min-Tsang; Chen, Hao-Ping; Lu, Chi-Cheng; Chiang, Jo-Hua; Wu, Tian-Shung; Kuo, Daih-Huang; Huang, Li-Jiau; Kuo, Sheng-Chu; Yang, Jai-Sing

The novel pterostilbene derivative ANK-199 induces autophagic cell death through regulating PI3 kinase class III/beclin 1/Atgrelated proteins in cisplatinresistant CAR human oral cancer cells.

Hsieh, Min-Tsang; Chen, Hao-Ping; Lu, Chi-Cheng; Chiang, Jo-Hua; Wu, Tian-Shung; Kuo, Daih-Huang; Huang, Li-Jiau; Kuo, Sheng-Chu; Yang, Jai-Sing.

Afiliación

Hsieh MT; School of Pharmacy, China Medical University, Taichung 404, Taiwan, R.O.C.
Chen HP; Department of Biochemistry, Tzu Chi University, Hualien 970, Taiwan, R.O.C.
Lu CC; Department of Food Science and Biotechnology, National Chung Hsing University, Taichung 402, Taiwan, R.O.C.
Chiang JH; Department of Chemistry, National Cheng Kung University, Tainan 701, Taiwan, R.O.C.
Wu TS; Department of Chemistry, National Cheng Kung University, Tainan 701, Taiwan, R.O.C.
Kuo DH; Department of Pharmacy and Graduate Institute of Pharmaceutical Technology, Tajen University, Pingtung 907, Taiwan, R.O.C.
Huang LJ; Graduate Institute of Pharmaceutical Chemistry, China Medical University, Taichung 404, Taiwan, R.O.C.
Kuo SC; Graduate Institute of Pharmaceutical Chemistry, China Medical University, Taichung 404, Taiwan, R.O.C.
Yang JS; Department of Pharmacology, China Medical University, Taichung 404, Taiwan, R.O.C.

Int J Oncol ; 45(2): 782-94, 2014 Aug.

Article en En | MEDLINE | ID: mdl-24889814

Asunto(s)

Antineoplásicos/farmacología; Autofagia/efectos de los fármacos; Resistencia a Antineoplásicos/efectos de los fármacos; Neoplasias de la Boca/metabolismo; Estilbenos/farmacología; Estilbenos/farmacocinética; Proteínas Reguladoras de la Apoptosis/metabolismo; Beclina-1; Western Blotting; Línea Celular Tumoral; Supervivencia Celular/efectos de los fármacos; Cisplatino/farmacología; Humanos; Proteínas de la Membrana/metabolismo; Neoplasias de la Boca/patología; Análisis de Secuencia por Matrices de Oligonucleótidos; Fosfatidilinositol 3-Quinasas/metabolismo; Reacción en Cadena de la Polimerasa

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Autofagia / Estilbenos / Neoplasias de la Boca / Resistencia a Antineoplásicos / Antineoplásicos Límite: Humans Idioma: En Revista: Int J Oncol Asunto de la revista: NEOPLASIAS Año: 2014 Tipo del documento: Article

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