Synthesis and SAR of Benzisothiazole- and Indolizine-ß-d-glucopyranoside Inhibitors of SGLT2.

Zhou, Huiqiang; Danger, Dana P; Dock, Steven T; Hawley, Lora; Roller, Shane G; Smith, Chari D; Handlon, Anthony L

Zhou, Huiqiang; Danger, Dana P; Dock, Steven T; Hawley, Lora; Roller, Shane G; Smith, Chari D; Handlon, Anthony L.

Afiliación

Zhou H; Metabolic Pathways Center of Excellence for Drug Discovery, GlaxoSmithKline, P.O. Box 13398, Research Triangle Park, North Carolina 27709-3398.
Danger DP; Metabolic Pathways Center of Excellence for Drug Discovery, GlaxoSmithKline, P.O. Box 13398, Research Triangle Park, North Carolina 27709-3398.
Dock ST; Metabolic Pathways Center of Excellence for Drug Discovery, GlaxoSmithKline, P.O. Box 13398, Research Triangle Park, North Carolina 27709-3398.
Hawley L; Metabolic Pathways Center of Excellence for Drug Discovery, GlaxoSmithKline, P.O. Box 13398, Research Triangle Park, North Carolina 27709-3398.
Roller SG; Metabolic Pathways Center of Excellence for Drug Discovery, GlaxoSmithKline, P.O. Box 13398, Research Triangle Park, North Carolina 27709-3398.
Smith CD; Metabolic Pathways Center of Excellence for Drug Discovery, GlaxoSmithKline, P.O. Box 13398, Research Triangle Park, North Carolina 27709-3398.
Handlon AL; Metabolic Pathways Center of Excellence for Drug Discovery, GlaxoSmithKline, P.O. Box 13398, Research Triangle Park, North Carolina 27709-3398.

ACS Med Chem Lett ; 1(1): 19-23, 2010 Apr 08.

Article en En | MEDLINE | ID: mdl-24900169

Palabras clave

Benzisothiazole- and indolizine-ß-d-glucopyranoside inhibitors; SAR; SGLT2; benzisothiazole-C-glucoside

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: ACS Med Chem Lett Año: 2010 Tipo del documento: Article Pais de publicación: Estados Unidos

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