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Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing.
Ding, Qiurong; Strong, Alanna; Patel, Kevin M; Ng, Sze-Ling; Gosis, Bridget S; Regan, Stephanie N; Cowan, Chad A; Rader, Daniel J; Musunuru, Kiran.
Afiliación
  • Ding Q; From the Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, MA (Q.D., S.-L.N., B.S.G., S.N.R., C.A.C., K.M.); Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity and Metabolism, and Cardiovascular Instit
  • Strong A; From the Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, MA (Q.D., S.-L.N., B.S.G., S.N.R., C.A.C., K.M.); Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity and Metabolism, and Cardiovascular Instit
  • Patel KM; From the Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, MA (Q.D., S.-L.N., B.S.G., S.N.R., C.A.C., K.M.); Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity and Metabolism, and Cardiovascular Instit
  • Ng SL; From the Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, MA (Q.D., S.-L.N., B.S.G., S.N.R., C.A.C., K.M.); Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity and Metabolism, and Cardiovascular Instit
  • Gosis BS; From the Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, MA (Q.D., S.-L.N., B.S.G., S.N.R., C.A.C., K.M.); Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity and Metabolism, and Cardiovascular Instit
  • Regan SN; From the Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, MA (Q.D., S.-L.N., B.S.G., S.N.R., C.A.C., K.M.); Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity and Metabolism, and Cardiovascular Instit
  • Cowan CA; From the Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, MA (Q.D., S.-L.N., B.S.G., S.N.R., C.A.C., K.M.); Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity and Metabolism, and Cardiovascular Instit
  • Rader DJ; From the Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, MA (Q.D., S.-L.N., B.S.G., S.N.R., C.A.C., K.M.); Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity and Metabolism, and Cardiovascular Instit
  • Musunuru K; From the Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, MA (Q.D., S.-L.N., B.S.G., S.N.R., C.A.C., K.M.); Institute for Translational Medicine and Therapeutics, Institute for Diabetes, Obesity and Metabolism, and Cardiovascular Instit
Circ Res ; 115(5): 488-92, 2014 Aug 15.
Article en En | MEDLINE | ID: mdl-24916110

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Serina Endopeptidasas / ARN Guía de Kinetoplastida / Edición de ARN / Proproteína Convertasas / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas / Hígado / Mutación Límite: Animals Idioma: En Revista: Circ Res Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Serina Endopeptidasas / ARN Guía de Kinetoplastida / Edición de ARN / Proproteína Convertasas / Repeticiones Palindrómicas Cortas Agrupadas y Regularmente Espaciadas / Hígado / Mutación Límite: Animals Idioma: En Revista: Circ Res Año: 2014 Tipo del documento: Article Pais de publicación: Estados Unidos