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A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12.
Duquet, Arnaud; Melotti, Alice; Mishra, Sonakshi; Malerba, Monica; Seth, Chandan; Conod, Arwen; Ruiz i Altaba, Ariel.
Afiliación
  • Duquet A; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
  • Melotti A; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
  • Mishra S; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
  • Malerba M; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
  • Seth C; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
  • Conod A; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland.
  • Ruiz i Altaba A; Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland Ariel.RuizAltaba@unige.ch.
EMBO Mol Med ; 6(7): 882-901, 2014 Jul.
Article en En | MEDLINE | ID: mdl-24920608

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Neoplasias del Colon / Proteínas de Transporte Vesicular / Proteínas Wnt / Factores de Transcripción TCF / Factores de Transcripción SOXC / Metástasis de la Neoplasia Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: EMBO Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2014 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Neoplasias del Colon / Proteínas de Transporte Vesicular / Proteínas Wnt / Factores de Transcripción TCF / Factores de Transcripción SOXC / Metástasis de la Neoplasia Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: EMBO Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2014 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Reino Unido