Warfarin-induced purple toe syndrome successfully treated with apixaban.
BMJ Case Rep
; 20142014 Jun 12.
Article
en En
| MEDLINE
| ID: mdl-24925541
ABSTRACT
Purple toe syndrome is a recognised adverse effect of warfarin therapy. The literature has described resolution of the ischaemic symptoms on withdrawal of the warfarin and switching to a low molecular weight heparin alternative. We present a case of an 82-year-old man with bilateral blanching vivacious toes and a livedo-reticularis type rash developing 2 weeks after being loaded with warfarin for first detected atrial fibrillation. Vascular surgical review and haematology thrombotic screen did not yield any other pathology and a diagnosis of purple toe syndrome due to warfarin was carried out. The warfarin was stopped and oral anticoagulation started with an oral factor Xa inhibitor, apixaban with resolution of his symptoms. This is the first case report of one of the novel oral anticoagulants being used to treat purple toe syndrome.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Pirazoles
/
Piridonas
/
Fibrilación Atrial
/
Warfarina
/
Dedos del Pie
/
Accidente Cerebrovascular
/
Inhibidores del Factor Xa
/
Isquemia
/
Anticoagulantes
Tipo de estudio:
Etiology_studies
Límite:
Aged80
/
Humans
/
Male
Idioma:
En
Revista:
BMJ Case Rep
Año:
2014
Tipo del documento:
Article
País de afiliación:
Reino Unido