Model system for targeted drug release triggered by immune-specific signals.
Anal Bioanal Chem
; 406(20): 4825-9, 2014 Aug.
Article
en En
| MEDLINE
| ID: mdl-24928114
ABSTRACT
A new sense-and-act system was realized by integrating a biocatalytic/bioaffinity electrode responding to immune signals represented by an antibody and a polymer-modified electrode loaded with drug-mimicking species. The release of the drug-mimicking species was achieved specifically in response to a signal antibody, thus demonstrating for the first time an immune-induced drug-releasing process. The present approach promises new options for future applications in controlled drug release and personalized medicine.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Anal Bioanal Chem
Año:
2014
Tipo del documento:
Article
País de afiliación:
Estados Unidos