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Drugging MYCN through an allosteric transition in Aurora kinase A.
Gustafson, William Clay; Meyerowitz, Justin Gabriel; Nekritz, Erin A; Chen, Justin; Benes, Cyril; Charron, Elise; Simonds, Erin F; Seeger, Robert; Matthay, Katherine K; Hertz, Nicholas T; Eilers, Martin; Shokat, Kevan M; Weiss, William A.
Afiliación
  • Gustafson WC; Department of Pediatrics, UCSF Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Meyerowitz JG; Departments of Neurology and Neurological Surgery, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, Univers
  • Nekritz EA; Department of Pediatrics, UCSF Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Chen J; Departments of Neurology and Neurological Surgery, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Benes C; Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA 02114, USA.
  • Charron E; Department of Pediatrics, UCSF Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA 94158, USA; Departments of Neurology and Neurological Surgery, University of California, San Francisco, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center
  • Simonds EF; Departments of Neurology and Neurological Surgery, University of California, San Francisco, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Seeger R; Division of Hematology/Oncology, Children's Hospital Los Angeles, 4650 Sunset Boulevard, Mailstop #57, Los Angeles, CA 90027, USA.
  • Matthay KK; Department of Pediatrics, UCSF Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Hertz NT; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Eilers M; Theodor Boveri Institute, Biocenter, University of Wurzburg, Am Hubland, 97074 Würzburg, Germany.
  • Shokat KM; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Weiss WA; Department of Pediatrics, UCSF Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA 94158, USA; Departments of Neurology and Neurological Surgery, University of California, San Francisco, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center
Cancer Cell ; 26(3): 414-427, 2014 Sep 08.
Article en En | MEDLINE | ID: mdl-25175806
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Fenilurea / Pirimidinas / Proteínas Nucleares / Proteínas Oncogénicas / Aurora Quinasa A / Neuroblastoma / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Fenilurea / Pirimidinas / Proteínas Nucleares / Proteínas Oncogénicas / Aurora Quinasa A / Neuroblastoma / Antineoplásicos Tipo de estudio: Prognostic_studies Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos