Cardiac cell lineages that form the heart.
Cold Spring Harb Perspect Med
; 4(9): a013888, 2014 Sep 02.
Article
en En
| MEDLINE
| ID: mdl-25183852
ABSTRACT
Myocardial cells ensure the contractility of the heart, which also depends on other mesodermal cell types for its function. Embryological experiments had identified the sources of cardiac precursor cells. With the advent of genetic engineering, novel tools have been used to reconstruct the lineage tree of cardiac cells that contribute to different parts of the heart, map the development of cardiac regions, and characterize their genetic signature. Such knowledge is of fundamental importance for our understanding of cardiogenesis and also for the diagnosis and treatment of heart malformations.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Linaje de la Célula
/
Miocitos Cardíacos
/
Corazón
/
Cardiopatías Congénitas
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Cold Spring Harb Perspect Med
Año:
2014
Tipo del documento:
Article
País de afiliación:
Francia