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Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: association with disease progression and influence of immune pressure.
Mann, Jaclyn K; Chopera, Denis; Omarjee, Saleha; Kuang, Xiaomei T; Le, Anh Q; Anmole, Gursev; Danroth, Ryan; Mwimanzi, Philip; Reddy, Tarylee; Carlson, Jonathan; Radebe, Mopo; Goulder, Philip J R; Walker, Bruce D; Abdool Karim, Salim; Novitsky, Vladimir; Williamson, Carolyn; Brockman, Mark A; Brumme, Zabrina L; Ndung'u, Thumbi.
Afiliación
  • Mann JK; HIV Pathogenesis Programme, University of KwaZulu-Natal, 719 Umbilo Road, Durban 4001, South Africa; KwaZulu-Natal Research Institute for Tuberculosis and HIV, University of KwaZulu-Natal, Durban 4001, South Africa.
  • Chopera D; HIV Pathogenesis Programme, University of KwaZulu-Natal, 719 Umbilo Road, Durban 4001, South Africa; KwaZulu-Natal Research Institute for Tuberculosis and HIV, University of KwaZulu-Natal, Durban 4001, South Africa; Institute of Infectious Disease and Molecular Medicine, and the Division of Medical
  • Omarjee S; HIV Pathogenesis Programme, University of KwaZulu-Natal, 719 Umbilo Road, Durban 4001, South Africa; KwaZulu-Natal Research Institute for Tuberculosis and HIV, University of KwaZulu-Natal, Durban 4001, South Africa.
  • Kuang XT; Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada V5A 1S6.
  • Le AQ; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada V5A 1S6.
  • Anmole G; Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada V5A 1S6.
  • Danroth R; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada V5A 1S6.
  • Mwimanzi P; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada V5A 1S6.
  • Reddy T; Medical Research Council, Biostatistics Unit, Durban 4001, South Africa.
  • Carlson J; Microsoft Research, Los Angeles, CA 90024, United States of America.
  • Radebe M; HIV Pathogenesis Programme, University of KwaZulu-Natal, 719 Umbilo Road, Durban 4001, South Africa; KwaZulu-Natal Research Institute for Tuberculosis and HIV, University of KwaZulu-Natal, Durban 4001, South Africa.
  • Goulder PJR; Department of Paediatrics, University of Oxford, Oxford OX1 3SY, United Kingdom; Ragon Institute of MGH, MIT and Harvard University, Cambridge, MA 02139, USA.
  • Walker BD; Ragon Institute of MGH, MIT and Harvard University, Cambridge, MA 02139, USA; Massachusetts General Hospital and Harvard University, Boston, MA 02114, USA; Howard Hughes Medical Research Institute, Chevy Chase, MD 20815, USA.
  • Abdool Karim S; Centre for the AIDS Programme of Research in South Africa, University of KwaZulu-Natal, Durban 4001, South Africa.
  • Novitsky V; Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA; Botswana-Harvard School of Public Health AIDS Initiative Partnership for HIV Research and Education, P/Bag BO 320, Gaborone, Botswana.
  • Williamson C; Institute of Infectious Disease and Molecular Medicine, and the Division of Medical Virology, University of Cape Town and National Health Laboratory Services, Cape Town 7925, South Africa.
  • Brockman MA; Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada V5A 1S6; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada V5A 1S6; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada V6Z 1Y6.
  • Brumme ZL; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada V5A 1S6; British Columbia Centre for Excellence in HIV/AIDS, Vancouver, BC, Canada V6Z 1Y6.
  • Ndung'u T; HIV Pathogenesis Programme, University of KwaZulu-Natal, 719 Umbilo Road, Durban 4001, South Africa; KwaZulu-Natal Research Institute for Tuberculosis and HIV, University of KwaZulu-Natal, Durban 4001, South Africa; Ragon Institute of MGH, MIT and Harvard University, Cambridge, MA 02139, USA; Max Pl
Virology ; 468-470: 214-225, 2014 Nov.
Article en En | MEDLINE | ID: mdl-25193656
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Genes MHC Clase I / Infecciones por VIH / Regulación de la Expresión Génica / VIH-1 / Productos del Gen nef del Virus de la Inmunodeficiencia Humana Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Virology Año: 2014 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Genes MHC Clase I / Infecciones por VIH / Regulación de la Expresión Génica / VIH-1 / Productos del Gen nef del Virus de la Inmunodeficiencia Humana Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Revista: Virology Año: 2014 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Estados Unidos