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Quantitative variation in la antigen expression plays a central role in immune regulation.
Janeway, C A; Bottomly, K; Babich, J; Conrad, P; Conzen, S; Jones, B; Kaye, J; Katz, M; McVay, L; Murphy, D B; Tite, J.
Afiliación
  • Janeway CA; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Bottomly K; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Babich J; Department of Pathology, Division of Immunology, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Conrad P; Department of Pathology, Division of Immunology, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Conzen S; Department of Pathology, Division of Immunology, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Jones B; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Kaye J; Department of Pathology, Division of Immunology, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Katz M; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06510, USA.
  • McVay L; Department of Pathology, Division of Immunology, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Murphy DB; Department of Pathology, Division of Immunology, Yale University School of Medicine, New Haven, CT 06510, USA.
  • Tite J; Department of Pathology, Division of Immunology, Yale University School of Medicine, New Haven, CT 06510, USA.
Immunol Today ; 5(4): 99-105, 1984 Apr.
Article en En | MEDLINE | ID: mdl-25291703
ABSTRACT
The analysis of la antigen function has focused primarily on allelic variants of Ia molecules. In this review Charles Janeway and his colleagues discuss evidence that quantitative rather than qualitative variation in Ia antigen expression had a major role in immunoregulation and immunologically mediated disease.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Qualitative_research Idioma: En Revista: Immunol Today Año: 1984 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Qualitative_research Idioma: En Revista: Immunol Today Año: 1984 Tipo del documento: Article País de afiliación: Estados Unidos