Sex-specific relationships between adverse childhood experiences and chronic obstructive pulmonary disease in five states.
Int J Chron Obstruct Pulmon Dis
; 9: 1033-42, 2014.
Article
en En
| MEDLINE
| ID: mdl-25298732
ABSTRACT
PURPOSE:
Adverse childhood experiences (ACEs) before age 18 have been repeatedly associated with several chronic diseases in adulthood such as depression, heart disease, cancer, diabetes, and stroke. We examined sex-specific relationships between individual ACEs and the number of ACEs with chronic obstructive pulmonary disease (COPD) in the general population. MATERIALS ANDMETHODS:
Data from 26,546 women and 19,015 men aged ≥18 years in five states of the 2011 Behavioral Risk Factor Surveillance System were analyzed. We used log-linear regression to estimate prevalence ratios (PRs) and their corresponding 95% confidence intervals (CIs) for the relationship of eight ACEs with COPD after adjustment for age group, race/ethnicity, marital status, educational attainment, employment, asthma history, health insurance coverage, and smoking status.RESULTS:
Some 63.8% of women and 62.2% of men reported ≥1 ACE. COPD was reported by 4.9% of women and 4.0% of men. In women, but not in men, there was a higher likelihood of COPD associated with verbal abuse (PR =1.30, 95% CI 1.05, 1.61), sexual abuse (PR =1.69, 95% CI 1.36, 2.10), living with a substance abusing household member (PR =1.49, 95% CI 1.23, 1.81), witnessing domestic violence (PR =1.40, 95% CI 1.14, 1.72), and parental separation/divorce (PR =1.47, 95% CI 1.21, 1.80) during childhood compared to those with no individual ACEs. Reporting ≥5 ACEs (PR =2.08, 95% CI 1.55, 2.80) compared to none was associated with a higher likelihood of COPD among women only.CONCLUSION:
ACEs are related to COPD, especially among women. These findings underscore the need for further research that examines sex-specific differences and the possible mechanisms linking ACEs and COPD. This work adds to a growing body of research suggesting that ACEs may contribute to health problems later in life and suggesting a need for program and policy solutions.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedad Pulmonar Obstructiva Crónica
/
Acontecimientos que Cambian la Vida
Tipo de estudio:
Clinical_trials
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Diagnostic_studies
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Etiology_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
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Middle aged
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Int J Chron Obstruct Pulmon Dis
Año:
2014
Tipo del documento:
Article
País de afiliación:
Estados Unidos