Ruthenium-catalyzed highly regio- and stereoselective hydroarylation of aromatic sulfoxides with alkynes via C-H bond activation.
Chem Commun (Camb)
; 50(93): 14573-6, 2014 Dec 04.
Article
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| MEDLINE
| ID: mdl-25307797
ABSTRACT
Chelation-assisted alkenylation at the ortho C-H bond of aromatic sulfoxides with alkynes in the presence of a ruthenium catalyst, AgSbF6 and pivalic acid yielding trisubstituted alkenes in good to excellent yields in a highly regio- and stereoselective manner via a deprotonation metalation pathway is described. Later, ortho-alkenylated aromatic sulfoxides were converted into α-acyloxy-thioether and a 2,3-disubstituted benzothiophene derivative.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2014
Tipo del documento:
Article
País de afiliación:
India