Hepatitis C virus infection in patients and family members attending two primary care clinics in Puebla, Mexico.
Ann Hepatol
; 13(6): 746-52, 2014.
Article
en En
| MEDLINE
| ID: mdl-25332260
ABSTRACT
BACKGROUND:
Approximately 180 million persons (~2.8%) globally are estimated to be infected by hepatitis C virus (HCV). HCV prevalence in Mexico has been estimated to be between 1.2 and 1.4%. The aim of present work was to determine the prevalence of HCV infection in patients and family members attending two primary care clinics in Puebla, Mexico. MATERIAL ANDMETHODS:
Patients and their accompanying family members in two clinics were invited to participate in this study between May and September 2010.RESULTS:
A total of 10,214 persons were included in the study; 120 (1.17%) persons were anti-HCV reactive. Of the reactive subjects, detection of viral RNA was determined in 114 subjects and 36 were positive (31%). The more frequent risk factors were having a family history of cirrhosis (33.1%) and having a blood transfusion prior to 1995 (29%). After a multiple logistic regression analysis only transfusion prior to 1995 resulted significant to HCV transmission (p = 0.004). The overall detected HCV genotypes were as follows 1a (29%), 1b (48.5%), 2/2b (12.8%), and 3a (6.5%).CONCLUSION:
The HCV prevalence in this population is in agreement with previous studies in other regions of Mexico.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Atención Primaria de Salud
/
ARN Viral
/
Hepatitis C
/
Anticuerpos contra la Hepatitis C
Tipo de estudio:
Etiology_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Mexico
Idioma:
En
Revista:
Ann Hepatol
Asunto de la revista:
GASTROENTEROLOGIA
Año:
2014
Tipo del documento:
Article