Degradable glycine-based photo-polymerizable polyphosphazenes for use as scaffolds for tissue regeneration.
Macromol Biosci
; 15(3): 351-63, 2015 Mar.
Article
en En
| MEDLINE
| ID: mdl-25355036
ABSTRACT
Photo-polymerizable scaffolds are designed and prepared via short chain poly(organo)phosphazene building blocks bearing glycine allylester moieties. The polyphosphazene was combined with a trifunctional thiol and divinylester in various ratios, followed by thiol-ene photo-polymerization to obtain porous matrices. Degradation studies under aqueous conditions showed increasing rates in correlation with the polyphosphazene content. Preliminary cell studies show the non-cytotoxic nature of the polymers and their degradation products, as well as the cell adhesion and proliferation of adipose-derived stem cells.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Compuestos Organofosforados
/
Polímeros
/
Regeneración
/
Rayos Ultravioleta
/
Ingeniería de Tejidos
/
Andamios del Tejido
/
Polimerizacion
/
Glicina
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Macromol Biosci
Asunto de la revista:
BIOQUIMICA
Año:
2015
Tipo del documento:
Article
País de afiliación:
Austria