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One small step for a yeast--microevolution within macrophages renders Candida glabrata hypervirulent due to a single point mutation.
Brunke, Sascha; Seider, Katja; Fischer, Daniel; Jacobsen, Ilse D; Kasper, Lydia; Jablonowski, Nadja; Wartenberg, Anja; Bader, Oliver; Enache-Angoulvant, Adela; Schaller, Martin; d'Enfert, Christophe; Hube, Bernhard.
Afiliación
  • Brunke S; Integrated Research and Treatment Center, Sepsis und Sepsisfolgen, Center for Sepsis Control and Care (CSCC), Universitätsklinikum Jena, Jena, Germany; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute Jena
  • Seider K; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute Jena (HKI), Jena, Germany.
  • Fischer D; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute Jena (HKI), Jena, Germany.
  • Jacobsen ID; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute Jena (HKI), Jena, Germany.
  • Kasper L; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute Jena (HKI), Jena, Germany.
  • Jablonowski N; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute Jena (HKI), Jena, Germany.
  • Wartenberg A; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute Jena (HKI), Jena, Germany.
  • Bader O; Institute for Medical Microbiology and German National Reference Centre for Systemic Mycoses, University Medical Centre Göttingen, Göttingen, Germany.
  • Enache-Angoulvant A; APHP, Hôpital Bicêtre, Service de Bactériologie-Virologie-Parasitologie, Laboratoire de Parasitologie-Mycologie, Kremlin-Bicêtre, France.
  • Schaller M; Department of Dermatology, Eberhard-Karls-University, Tübingen, Germany.
  • d'Enfert C; Institut Pasteur, Unité Biologie et Pathogénicité Fongiques, Département Génomes et Génétique, Paris, France; INRA, USC2019, Paris, France.
  • Hube B; Integrated Research and Treatment Center, Sepsis und Sepsisfolgen, Center for Sepsis Control and Care (CSCC), Universitätsklinikum Jena, Jena, Germany; Department of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knoell Institute Jena
PLoS Pathog ; 10(10): e1004478, 2014 Oct.
Article en En | MEDLINE | ID: mdl-25356907
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Candidiasis / Adaptación Fisiológica / Polimorfismo de Nucleótido Simple / Candida glabrata / Macrófagos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: PLoS Pathog Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Candidiasis / Adaptación Fisiológica / Polimorfismo de Nucleótido Simple / Candida glabrata / Macrófagos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: PLoS Pathog Año: 2014 Tipo del documento: Article