Roles of miR-497 and its potential signaling pathway in diseases and with vascular endothelial growth factor.
J Recept Signal Transduct Res
; 35(4): 303-6, 2015.
Article
en En
| MEDLINE
| ID: mdl-25366590
ABSTRACT
MicroRNA (miRNA) is a class of small endogenous non-coding RNAs that are â¼ 22 nucleotides in length and can have structural, enzymatic and post-transcriptional regulators of gene expression targeting mRNA for translational repression and/or degradation. miR-497 is high on the list of noncoding, small, regulatory RNAs that plays important roles in the pathogenesis of some diseases and takes part in some signaling pathways in some diseases, but many questions await answers. Vascular endothelial growth factor (VEGF) is a notable chemokine that plays critical roles in angiogenesis and vasculogenesis. There might be an association between miRNA-497 and VEGF. This review was performed to sum up the roles of miR-497 and its potential signaling pathway in diseases and with VEGF.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
MicroARNs
/
Factor A de Crecimiento Endotelial Vascular
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Recept Signal Transduct Res
Asunto de la revista:
BIOQUIMICA
/
FISIOLOGIA
Año:
2015
Tipo del documento:
Article