Quantitative analysis on collagen of dermatofibrosarcoma protuberans skin by second harmonic generation microscopy.
Scanning
; 37(1): 1-5, 2015.
Article
en En
| MEDLINE
| ID: mdl-25369371
ABSTRACT
Dermatofibrosarcoma protuberans (DFSP) is a skin cancer usually mistaken as other benign tumors. Abnormal DFSP resection results in tumor recurrence. Quantitative characterization of collagen alteration on the skin tumor is essential for developing a diagnostic technique. In this study, second harmonic generation (SHG) microscopy was performed to obtain images of the human DFSP skin and normal skin. Subsequently, structure and texture analysis methods were applied to determine the differences in skin texture characteristics between the two skin types, and the link between collagen alteration and tumor was established. Results suggest that combining SHG microscopy and texture analysis methods is a feasible and effective method to describe the characteristics of skin tumor like DFSP.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Piel
/
Neoplasias Cutáneas
/
Colágeno
/
Dermatofibrosarcoma
/
Microscopía
Tipo de estudio:
Diagnostic_studies
/
Evaluation_studies
Límite:
Humans
Idioma:
En
Revista:
Scanning
Año:
2015
Tipo del documento:
Article
País de afiliación:
China