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A phase I monotherapy study of RG7212, a first-in-class monoclonal antibody targeting TWEAK signaling in patients with advanced cancers.
Lassen, Ulrik N; Meulendijks, Didier; Siu, Lilian L; Karanikas, Vaios; Mau-Sorensen, Morten; Schellens, Jan H M; Jonker, Derek J; Hansen, Aaron R; Simcox, Mary E; Schostack, Kathleen J; Bottino, Dean; Zhong, Hua; Roessler, Markus; Vega-Harring, Suzana M; Jarutat, Tiantom; Geho, David; Wang, Ka; DeMario, Mark; Goss, Glenwood D.
Afiliación
  • Lassen UN; Department of Oncology, The Finsen Centre, Rigshospitalet, Copenhagen, Denmark. ulrik.lassen@rh.regionh.dk.
  • Meulendijks D; Department of Clinical Pharmacology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Siu LL; Ontario Cancer Institute/Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
  • Karanikas V; Roche Pharmaceutical Research and Early Development, Translational Medicine Oncology, Roche Innovation Center Zurich, Schlieren, Switzerland.
  • Mau-Sorensen M; Department of Oncology, The Finsen Centre, Rigshospitalet, Copenhagen, Denmark.
  • Schellens JH; Department of Clinical Pharmacology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Jonker DJ; Ottawa Hospital Cancer Center, Ottawa, Ontario, Canada.
  • Hansen AR; Ontario Cancer Institute/Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
  • Simcox ME; Roche Translational Clinical Research Center Inc., New York, New York.
  • Schostack KJ; Roche Translational Clinical Research Center Inc., New York, New York.
  • Bottino D; Roche Translational Clinical Research Center Inc., New York, New York.
  • Zhong H; Roche Translational Clinical Research Center Inc., New York, New York.
  • Roessler M; Roche Diagnostics GmbH, Penzberg, Germany.
  • Vega-Harring SM; Roche Diagnostics GmbH, Penzberg, Germany.
  • Jarutat T; Roche Diagnostics GmbH, Penzberg, Germany.
  • Geho D; Roche Translational Clinical Research Center Inc., New York, New York.
  • Wang K; Roche Translational Clinical Research Center Inc., New York, New York.
  • DeMario M; Roche Translational Clinical Research Center Inc., New York, New York.
  • Goss GD; Ottawa Hospital Cancer Center, Ottawa, Ontario, Canada.
Clin Cancer Res ; 21(2): 258-66, 2015 Jan 15.
Article en En | MEDLINE | ID: mdl-25388164
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Melanoma / Anticuerpos Monoclonales / Antineoplásicos Tipo de estudio: Clinical_trials Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2015 Tipo del documento: Article País de afiliación: Dinamarca
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Melanoma / Anticuerpos Monoclonales / Antineoplásicos Tipo de estudio: Clinical_trials Límite: Female / Humans / Male / Middle aged Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2015 Tipo del documento: Article País de afiliación: Dinamarca