Beyond autonomic neuromodulation: acetylcholinesterase inhibitor against peripheral artery disease.
Int J Cardiol
; 178: 253-5, 2015 Jan 15.
Article
en En
| MEDLINE
| ID: mdl-25464264
ABSTRACT
The acetylcholinesterase inhibitor (AChEI)-based therapeutic strategies have been shown to have vasculoprotective properties in the animal model of hindlimb ischemia due to its activation of the endothelial cholinergic system. However, little is know about whether other cell types (myocytes, immunocytes) are involved in the AChEI-related therapeutic benefits in peripheral artery disease. Therefore, we review the multiple cell-targeted effects of AChEI on the animal model of hindlimb ischemia and explore its clinical application in angiomyogenesis.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Inhibidores de la Colinesterasa
/
Enfermedad Arterial Periférica
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Int J Cardiol
Año:
2015
Tipo del documento:
Article