Evaluation of orange-brown precipitate formed in root canals after irrigation with chlorhexidine and QMix and spectroscopic analysis of precipitates produced by a mixture of chlorhexidine/NaOCl and QMix/NaOCl.
Int Endod J
; 48(12): 1199-203, 2015 Dec.
Article
en En
| MEDLINE
| ID: mdl-25557836
ABSTRACT
AIMS:
(i) To compare chlorhexidine and QMix(TM) in terms of orange-brown precipitate generation in root canals and (ii) to analyse the precipitate produced by mixing chlorhexidine and QMix(™) with NaOCl to determine whether para-chloroaniline was produced.METHODOLOGY:
The root canals of 57 single-rooted anterior teeth were prepared using ProTaper Universal rotary instruments up to size F4. Two millilitres of 2.5% NaOCl was used between each instrument change. The specimens were then divided randomly into three groups (n = 19) and irrigated as follows group 1, 5 mL of distilled water (control group) for 60 s; group 2, 5 mL of 2% chlorhexidine for 60 s; and group 3, 5 mL of QMix for 60 s. The roots were split longitudinally, and one of the halves was photographed using a stereomicroscope. The amount of orange-brown precipitate was evaluated using a four-grade scoring system. The data were analysed statistically using the Kruskal-Wallis and Mann-Whitney U-tests (P = 0.05). To evaluate whether the precipitates included para-chloroaniline, 5 mL of 2% chlorhexidine and 5 mL QMix were separately mixed with 5 mL of 2.5% NaOCl in two flasks. After centrifugation, precipitates were obtained and analysed using (1) H NMR spectra. The data were subjected to statistical analysis using the Kruskal-Wallis and Mann-Whitney tests at a 95% confidence level (P = 0.05).RESULTS:
Chlorhexidine had significantly higher scores than QMix(™) in terms of orange-brown precipitate formed in the root canals (P < 0.001). According to the 1H NMR spectra, para-chloroaniline was present in the mixture of chlorhexidine and NaOCl. However, the mixture of QMix(™) and NaOCl did not result in para-chloroaniline formation.CONCLUSION:
QMix(™) does not form para-chloroaniline when associated with NaOCl.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Polímeros
/
Irrigantes del Conducto Radicular
/
Hipoclorito de Sodio
/
Biguanidas
/
Clorhexidina
/
Cavidad Pulpar
/
Compuestos de Anilina
Tipo de estudio:
Evaluation_studies
Límite:
Humans
Idioma:
En
Revista:
Int Endod J
Año:
2015
Tipo del documento:
Article
País de afiliación:
Turquía